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Cardiovascular Health
Introduction
 
This group is involved in those research activities which contribute to improving clinical practice in the treatment of a range of cardiovascular diseases.  Our specialist areas include the measurement of cardiac power output, heart rate variability, cardiac rehabilitation and metabolic changes during exercise.  Much of our research is laboratory based, but increasingly we are working in clinical environments.  Recently, patients included those with peripheral vascular disease, those who are post myocardial infarction, patients with heart failure and asthmatics. 
 
Group Members
 
David Brodie (Group Leader) (david.brodie@bucks.ac.uk)
Gay Donovan
Lin Guo

Keiran Henderson
Lynette Hodges (Massay University)
Djordje Jakovljevic
Nasim Kanji
Nonsi Mathe
Johana Nayoan
David Nunan
Jeyasunder Radhakrishnan
Gavin Sandercock (Essex University)
Chris Shelton
Colin Slattery
Sue West

Research Students
 
Gay Donovan PhD registration

Effects of specific interventions on selected cardio-respiratory markers in patients with moderate to severe heart failure

Lin Guo MPhil/PhD registration
The impact of specific interventions on cardiovascular and other health measures with corporate clients

Djordje Jakovljevic PhD registration
The effects of specific interventions on cardiac power output and selected cardio-respiratory variables in patients with moderate to severe heart failure

Nonsi Mathe PhD registration
Adiposity and cardiovascular disease risk factors: a comparison between ethnic groups 

Johana Nayoan PhD registration
Self-regulation and quality of life in first-time myocardial infarction:  a cross-cultural study

Jeyasundar Radhakrishnan MPhil/PhD registration
Changes in erectile dysfunction following cardiac rehabilitation

Selected Publications


Brodie, D.A., Inoue, A., Shaw, D., Aimson, P. 2008. Motivational interviewing to change quality of life for people with chronic heart failure:  a randomised controlled trial. International Journal of Nursing Studies, 45(4), 489-500

Brodie, D.A., Bethell, H., and Breen, S. 2006. Cardiac rehabilitation in England: a detailed national survey. European Journal of Cardiovascular Prevention and Rehabiliation, 13(1), 122-128

Brodie, D.A. and Inoue, A, 2005, Motivational interviewing to promote physical activity for people with chronic heart failure. Journal of Advanced Nursing, 50(5), 518-527

Khassaf, M., McArdle, A., Esanu, C., Vasilaki, A., McArdle, F., Griffiths, R.D., Brodie, D.A., and Jackson, M.J. 2003. Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle. The Journal of Physiology, 549.2, 645-652.

Brodie, D.A., Liu, X., and Jackson, M. 2003. Changes in serum biochemical responses during cardiac rehabilitation. Medicine & Science in Sports & Exercise, 35(5), 741-746.

Delaney, J.P.A., Leong, K.S., Watkins, A., and Brodie, D.A. 2002. The short-term effects of myofascial trigger point massage therapy on cardiac autonomic tone in healthy subjects. Journal of Advanced Nursing, 37(4) 364-371.

Khassaf, M., Child, R.B., McArdle, A., Brodie, D.A., Esanu, C., and Jackson, M.J. 2001. Time course of responses of human skeletal muscle to oxidative stress induced by nondamaging exercise. Journal of Applied Physiology, 90, 1031-1035.

Brodie, D.A., Liu, X., and Bundred, P.E. 2001. Effects of blood pressure, blood cholesterol and smoking on the functional capacity of post myocardial infarction patients in the early stages of cardiac rehabilitation. Coronary Health Care, 5(2), 61-66.

Selected Presentations

Brodie, D. A. 2008. Caring for the underserved in the UK:  evidence from ongoing research at BUCKSNew University, 16th Annual Conference, Caring for the Underserved:  A Global Perspective, Northeastern University, Boston, Massachusetts.  11-13 December 2008, Keynote Lecture

Jakovljevic, D., Donovan, G., Nunan, D., George, R., Bougard, R., Birks, E., Yacoub, M., Brodie, D.A. 2008. Relationship between peak cardiac power output and selected cardiopulmonary variables in patients on left ventricular assist devices, explanted (recovered) patients and those with severe heart failure, European Cardiac Society Heart Failure Congress, Milan, Italy.  14-17 June 2008

Brodie, D.A., Hodges, L., Kirby, M. 2008. Cardiovascular risk in patients with erectile dysfunction, 9th Congress of the European Federation of Sexology, Therapy, Prevention and Promotion of Sexual Well-Being, Cavalier Hotel, Rome.  13-17 April 2008

Nunan, D., Donovan, G., Jakovljevic, D., Sandercock, G.R.H., George, R., Bougard, R., Birks, E., Yacoub, M., Brodie, D. A. 2008.  Normalisation of autonomic dysfunction in patients following recovery using left ventricular assist device combination therapy, The International Society for Heart and Lung Transplatation. 28th Annual Meeting and Scientific Conference, Hynes Convention Center and Boston Marriott Copley Place,  Boston, Massacheusetts, USA.  9-12 April 2008

Brodie, D.A.  2003.  Motivational interviewing: The role of the nurse in promoting physical activity in elderly heart failure patients. Annual International Nursing Research Conference, UMIST, Manchester, April 2003.

Upton J., Beales, D., Brodie, D.A. and Richardson J.  Dysfunctional breathing in asthma: a pilot study.  International Society for the Advancement of Respiratory Psychophysiology.  Leuven 22-24 September 2003.

Beales D., Upton J. and Brodie D.A.  The relationship between psychological well being and capnography profiling in people with asthma.  International Society for the Advancement of Respiratory Psychophysiology.  Leuven 22-24 September 2003.

Brodie, D.A., 2003.  The effectiveness of patient centred motivational interviewing for patients with chronic disease.  The Royal Collegeof General Practitioners, London, September 2003.

Brodie D.A.  UK Federation of Primary Care Research Networks.  Cardiovascular Disease Research Interest Group Meeting.  The Fielder Centre, Hatfield, Hertfordshire. 13 September 2002.

Inoue, A., Brodie, D.A., and Lye, M.  2001.  The use of patient-practitioner negotiation to promote physical activity in an elderly population with chronic heart failure.  BACR Meeting, Blackpool, 26-28 September 2001.

Collaborators
 
University College London (Dr. H.E. Montgomery, Dr. S.D. Dhamrait and Dr. J.R. Payne)
Imperial College London and Hillingdon Hospital (Mr. S. Das and R. Grocott-Mason)
Royal Brompton and Harefield NHS Trust (Dr. J. Hardy and Prof. Sir M. Yacoub)
Coronary Prevention Group (Dr. H. Bethell)
Hertfordshire Primary Care Research Network (Dr. M. Kirby)